21-year-old Sam and 20-year-old Caitlyn hit the road, encountering patients with breathing difficulties, patients in care homes, and patients with mental health issues. Caitlyn falls ill with Covid-19 symptoms and needs an urgent test for the virus.

As the coronavirus sweeps across the country, it brings with it a wave of fear and anxiety. While Jim counsels people who are struggling with self-isolation, Karina and James respond to a call from a man who claims to be armed and threatens suicide.

As the UK enters its fourth week of lockdown, the ambulance service comes to the aid of the staff of care homes, who are feeling forgotten as the virus claims the lives of so many residents.