A classic case of Munchausen Syndrome by Proxy, Genene Jones killed at least 47 patients with the muscle relaxant succinylcholine while working at Bexar Medical Center in Texas. She loved creating emergencies, the excitement of a ""code blue"" and especially the reactions of family members when told of the death of a loved one.

Nine hundred children are sent home from school and thousands inoculated during an outbreak in Massachusetts that depletes local supplies of antibiotics and lands four middle school students in the hospital. Ten-year-old Kayla St. Pierre spends ten days in critical care and loses all of her fingers and both legs to the disease.

An unassuming male nurse from Kentucky comes under scrutiny when hospital officials notice that death is unusually prominent during his work shifts. In fact, death seemed to follow Donald Harvey from job to job, beginning in 1970 and ending with his arrest in 1987.

Dr. Harold ""Fred"" Shipman was known as a dedicated, hardworking and community-minded doctor who spent his life gaining the trust of his patients and the respect of his colleagues. And for 25 years, nobody suspected that the town doctor was amassing a death toll that would make him one of history's most prolific serial killers.

Reverend Dwight Moore is at death's door when he is transferred from his local hospital to Memorial Hospital in Chapel Hill. With all the expertise and technology of modern medicine at their disposal, doctors are still unable to find of the cause of Moore's symptoms, which include stomach pain, numbness, and hallucinations.

In an exclusive Kansas City suburb, cardiologist Mike Farrar is suddenly stricken with a powerful and mysterious stomach illness. The violent and terrifying symptoms are relentless, leaving the man fighting for his life. Mike's doctors fight to save him, but they struggle to find the source of the disease that is making him waste away before their eyes.

Phil Rouss realizes a lifelong dream when he opens an antique auto restoration business with his long-time friend Steve White. They divide the work - Rouss will restore the cars and Steve will handle the books. The business is an immediate success, but within weeks Rouss is struck down with a mysterious illness.

Robert Curley is newly married and is renovating an old home for he and his wife, Joann. He is also an electrician doing repair work in a local chemistry lab. Within weeks of starting the new projects he becomes violently ill. His feet and hands tingle for no apparent reason. Doctors diagnosis his ailment and send him home with medication, but that doesn't work.

Donna Boley of St. Louis, Missouri, has suffered flu-like symptoms for months. One day she's rushed to the hospital with organ failure and becomes paralyzed from the neck down. Tests show astronomical levels of arsenic in her urine.

When two young children in Idaho are diagnosed with food poisoning, doctors have no idea that within days the situation will get out of control, as two hundred thousand people fall ill in the country's largest case of single source food poisoning.