A college professor who believes there's no place for jealousy in modern marriage, John Hathaway (Don Ameche) moves with his wife, Julie (Rosalind Russell), to New York where he plans to publish a book on the subject. Meeting with publisher Elliott Morgan (Van Heflin), who falls head over heels for Julie, John is assigned to his assistant Nellie (Kay Francis), who only has eyes for her boss. Working closely with Nellie, who Julie thinks is after her husband, John continues his high-minded ways while his angry spouse schemes to make him so jealous he'll knock Elliott's block clean off.

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